Read the immune system in high resolution

Immune repertoire mapping at cellular resolution.

OS-T

Quantity. Quality.

Map complete T cell response:
Up to 1 million T cells per clinical sample

OS-B

Something.

Improve therapy.

OS-IP

Accessible. Actionable.

Browsable immune portal:
Identify biomarkers with intuitive data analysis.

OS-T

Sequence up to 1 million T cells per clinical sample.

Obtain ultra-deep and single-cell resolved T cell repertoire profiles with advanced cell capture and indexing strategies.

With 500 million years of evolution, the immune system is the best tool when it comes to detecting and fighting against disease. By extracting information contained within immune cells, you obtain a more holistic and complete view of the patient’s status.

We each have ≈1011 unique T cells which represents an incredible diversity.

Sequencing at scale & precision is required to not miss out on specific T cell(s), and to utilize our immune system as a diagnostic sensor and therapeutic.

Analyze up to 1 million T Cell Receptors (TCRs) from one clinical sample mapping personal immunity at depth and breadth.

Sequence full VDJ gene segments responsible for diversity and obtain sequences of paired alpha-beta chains.

Count, detect, and characterise clonotypes.

Track disease response longitudinally.

OS-T

Universal platform to inform novel therapeutics and develop informative diagnostics.

How to apply OS-T?
High Resolution
With full VDJ sequences as well as Alpha / Beta pairing you obtain a full view of the immune response and correlate disease-specific epitopes to characterized diseases.
Map individual TCRs to detect disease-specific signatures from a single sample.
Accurate + Precise
Being accurate and precise means that you can identify prognostic and therapeutic cells to design companion diagnostics and develop cell therapies.
Select specific T cells with high accuracy and precision.
Less invasive
OS-T enables a less invasive way to detect diseases, inform treatment efficacy, and monitor immune system response to therapy.
Capture depth and breadth of personal immunity from one clinical sample.
AI powered
Disease AI/ML models enables acceleration of drug development, prediction of outcomes, and design of therapeutic cells.
More data results in better AI/ML disease models.

OS-IP

From data to clinical insights.

Access cellular resolution resolved data sets spanning multiple disease areas and therapeutic scenarios with OS-IP’s growing Disease Library.

Download formatted raw data files (.csv)

Leverage interactive analysis reports to extract clinical information, customized to accelerate therapy development and optimise clinical trials.

Search clonotype sequences and epitope annotation across databases.

OS-IP

Omniscope Immune Portal

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Applications

Gain a holistic view of immune system dynamics to inform vaccine development, measure therapy efficacy, and for haematological malignancies detect early traces of disease.

OS-VAX

Comprehensive.

Accelerate vaccine development.

OS-IMT

Predictive.

Identify therapy response.

OS-MRD

Sensitive.

Monitor disease recurrence.